Many things can trigger debilitating depression. Feelings of depression are caused by a chemical change that affects how the brain functions.

A normally functioning brain is a giant messaging system that controls everything from your heartbeat, to walking, to your emotions. The brain is made up of billions of nerve cells called neurons. These neurons send and receive messages from the rest of your body, using brain chemicals called neurotransmitters.

These brain chemicals—in varying amounts—are responsible for our emotional state. Depression happens when these chemical messages aren’t delivered correctly between brain cells, disrupting communication.

Think of a telephone: if your phone has a weak signal, you may not hear the person on the other end. Their communication is muted or unclear.

The good news is that there are many forms of treatment that can help you cope with depression, including medications that can strengthen weak signals by raising the levels of certain neurotransmitters, or by improving the neurons’ ability to process signals. This ensures that the brain’s vital messages are delivered—loud and clear.
Some people say that depression feels like a black curtain of despair coming down over their lives. Many people feel like they have no energy and can't concentrate. Others feel irritable all the time for no apparent reason. The symptoms vary from person to person, but if you feel "down" for more than two weeks, and these feelings are interfering with your daily life, you may be clinically depressed.

Most people who have gone through one episode of depression will, sooner or later, have another one. You may begin to feel some of the symptoms of depression several weeks before you develop a full-blown episode of depression. Learning to recognize these early triggers or symptoms and working with your doctor will help to keep the depression from worsening.

Most people with depression never seek help, even though the majority will respond to treatment. Treating depression is especially important because it affects you, your family, and your work. Some people with depression try to harm themselves in the mistaken belief that how they are feeling will never change. Depression is a treatable illness.
Life with depression

Working with your doctor, you can learn to manage depression. You may have to try a few different medications to find the one that works best for you. Your doctor may also recommend that you see a therapist and/or make certain lifestyle changes.

Change won't come overnight—but with the right treatment, you can keep depression from overshadowing your life.

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