FLIM Microscopy in Biology and Medicine



* Publisher: Chapman & Hall/CRC
* Number Of Pages: 472
* Publication Date: 2009-07-06
* ISBN-10 / ASIN: 1420078909
* ISBN-13 / EAN: 9781420078909

Product Description:
Detecting Signals at the Single Molecule Level: Pioneering Achievements in Microscopy
Recent advances have led to such remarkable improvements in fluorescence lifetime imaging microscopy’s (FLIM) capacity for contrast and sensitivity that researchers can now employ it to detect signals at the single molecule level. FLIM also offers the additional benefit of independence from fluorophore concentration and excitation intensity. Moreover, its unique sensitivity makes it an excellent reporter of conformational changes and of variations in the molecular surroundings of biological molecules.
Most of this improvement and discovery have occurred during the past decade, and, to date, information that would benefit a broad range of researchers remains scattered in the literature. Edited by two of the top pioneers in the field, FLIM Microscopy in Biology and Medicine presents the fundamentals of FLIM along with a number of advanced considerations so that a wider audience can appreciate recent and potential improvements that make it such a valuable tool.

[Only registered and activated users can see links. ]